Skip to contents

an interface function to run GLRT for all exons in multiple genes for multiple cell group pairs from a Splice object.

Usage

# S4 method for Splice,character,list,list
genes_groups_GLRT(object, genes, group1s, group2s, ...)

Arguments

object

the Splice object

genes

a vector of gene names to do GLRT

group1s

a named list of cell names, each element should be cells belonging to a group

group2s

a named list of cell names, each element should be cells belonging to a group

...

other parameters for gene_GLRT.base

Value

a dataframe of the test result. Each line is an exon with p-values and parameters for the psi distributions in two cell populations if they have significant difference