graph_clone_ot — graph_clone

Parallel Clone-to-Clone OT Computation on Cell Graph

Usage

graph_clone_ot(graph, cell_clone_prob, cache = 5000, cores = 1)

Arguments

graph: An `igraph` object representing the cell-cell distance graph.
cell_clone_prob: A matrix of clone membership probabilities (cells × clones).
cache: Integer. Maximum number of pooled cells retained in memory during each subgraph operation (default: 5000).
cores: Integer. Number of parallel threads to use (default: 1).

Value

A data frame with columns `group1`, `group2`, and `dis` representing OT distances between clone pairs.

Details

Computes clone-to-clone optimal transport (OT) distances in parallel by first partitioning clones and applying `graph_clone_ot_sub()` on each group. Supports memory-efficient computation with subset caching.