graph_clone_ot_sub — graph_clone_ot

Compute Pairwise OT Distances Between Clones Using Graph-Based Subset Strategy

Usage

graph_clone_ot_sub(graph, cell_clone_prob, target_clone = NULL, cache = 5000)

Arguments

graph: An `igraph` object representing cell-cell distances.
cell_clone_prob: A matrix of clone membership probabilities (cells × clones).
target_clone: Optional. Vector of clone indices to compute pairwise OT from (default: `NULL` = all).
cache: Integer. Maximum number of pooled cells retained in memory during iteration (default: 5000).

Value

A matrix with columns: `group1`, `group2`, `dis` for each clone pair and their OT distance.

Details

Computes clone-to-clone optimal transport distances by expanding a local graph-based cell neighborhood using a subset pool strategy to reduce computational burden.